Tagged: IBS

IBS – Irritable Bowel Syndrome

Posted on March 21, 2017

Irritable bowel syndrome (IBS) affects 25-45 million Americans

Do you or someone you know have irritable bowel syndrome (IBS)?

We may be able to help.

What is IBS?

  • IBS is a group of digestive symptoms including abdominal pain or discomfort improved by passing stool. Bowel irregularity (either diarrhea or constipation)
  • It is not life threatening, and it does not progress into more serious diseases. However, it can definitely affect your qualify of life.

IBS is very common, affecting 25-45 million Americans, mostly women starting in the late teens. It is the second most common cause for missing work and is associated with a higher risk of gall bladder surgery and hysterectomy.

There are three types of IBS:

  • IBS-Constipation
  • IBS-Diarrhea
  • IBS-Alternating constipation with diarrhea


There are multiple possible causes including: 

  • Gut to brain communication defect
  • Hypersensitivity of the gut
  • Altered bacteria in the gut
  • Leaky gut
  • Serotonin problems
  • Post-infectious IBS
  • Hormones and stress may be a factor, but not a cause

How to diagnose:

There is no specific test, so some believe you must rule out other diseases (Crohn’s, Microscopic Colitis, Celiac, etc.). However, there is a blood test to determine if you have post-infectious IBS.


  • Avoid food that may trigger your symptoms
  • Avoid caffeine
  • Add more fiber
  • Drink more water
  • Stop smoking
  • Exercise
  • Reduce stress
  • Watch for lactose intolerance or gluten intolerance


  • Anti-Spasmodic may help cramps
  • Anti-Diarrheal may help diarrhea
  • Low dose antidepressant for pain
  • Linzess for IBS-Constipation
  • Viberza for IBS-Diarrea
  • Xafaxan for IBS-Diarrhea
  • OTC IBgard for IBS-D
  • Enteragam OTC for IBS-Diarrhea
  • Probiotics

ClinSearch is always doing studies for patients with irritable bowel syndrome. To see if you qualify, call (423) 698-4584.

Inside Insights from Spaz the Spastic Colon.

Posted on February 4, 2016

Happy Colon


My name is Spaz, and I’m a Spastic Colon. I am a hard worker with good intentions, but sometimes I have anger issues. This happens to be pretty common for those of us in the “business”. Did you know that nearly 15% of all the bowels in the United States have a reputation for being irritable? Unfortunately, when tummies get upset we can be a literal pain in the butt. That’s why it’s important to understand what provokes us. I have taken it upon myself to be the voice of intestines everywhere in hopes that one day we can all live in digestive peace.

Colons are sensitive beings. Second only to the brain, the digestive tract contains the largest number of nerve cells in the entire body. It’s safe to say that I have a mind of my own. (Click here to learn more about my brain, aka the Enteric Nervous System.) There are multiple interacting factors that have an effect on us, and some of us are especially hypersensitive.

Spastic Colon

Things that make me go “Grrr”

#1. Communication Issues

I’m not totally blaming the “big brain” upstairs, but I’d say that one of the underlying problems is the way she processes the sensory information I send her. We don’t always have the best communication and that can be very frustrating for both of us.

#2. Bacterial Imbalance (Dysbiosis)

Happy intestines have a healthy balance of both good and bad bacteria.  There is a constant battle going on down here between them.  In the event that a colony takes over, a chronic imbalance occurs, known as dysbiosis.  This is actually a very important insight into my psyche.  Many of the symptoms of IBS (and a host of other ailments, mental and physical) are believed to stem from intestinal dysbiosis.

#3. Leaky Gut Syndrome

Now seems like a good time to address Leaky Gut Syndrome. A leaky gut is an unhappy gut and arguably more of a symptom than a diagnosis. The small intestine is expected to simultaneously function as a sponge AND a barrier, absorbing nutrients while keeping food, bacteria and other unsavory molecules from entering the bloodstream. Leaky guts struggle with this and are often found in patients with Crohn’s, Celiac Disease and IBS. While the cause isn’t always clear the effects can lead to many problems throughout your entire body. Including but not limited to: inflammatory bowel disease; food allergies; and chronic skin problems.

There you have it folks. I hope I was able to provide some insight from the inside. Next time you think your tummy is upset, maybe you’ll have a better understanding of why. For more information on IBS, treatment options, and when to see a doctor click here.

ClinSearch has provided our community with access to clinical research trials since 1992. We serve volunteers from the greater Chattanooga area, Cleveland, Dalton, Georgia and North-Eastern Alabama with access to clinical trials like this one, currently enrolling for Crohn’s Disease. While each individual trial varies, most offer study-related investigational drug and medical exams at no cost, and compensation for your time and travel.

ClinSearch is always looking for qualified volunteers. If you have IBS, Crohn’s, Celiac Disease, or any other inflammatory bowel disorder and want to know more about new treatment options, give us a call at (423) 698-4584 or request more information here.

Irritable Bowel Syndrome: Did you know?

Posted on August 18, 2015

By Melissa Watson



Do you suffer from Irritable Bowel Syndrome?  You’re not alone.  It is estimated that nearly 32-48 million people in the United States have IBS.  While so many share this affliction, only 53% of patients are satisfied with their current IBS treatment.  Want to learn more about IBS?  Keep reading.  I’ll touch on everything from possible causes, when to see a doctor, and lifestyle changes that can help you manage your angry gut.

 Everybody poops.  But if your quality of life has been affected by your bathroom habits, you may have Irritable Bowel Syndrome.  Other symptoms include:

  • Abdominal discomfort that usually improves with passage of stool.
  • Bloating
  • Constipation and/or
  • Diarrhea


Why me?  Some interesting facts about IBS and possible causes.

  • IBS is more common in women than men
  • While it’s unusual to develop the disorder after 50, the average age of sufferers is 46.
  • 40% have diarrhea
  • 35% have constipation
  • 25% have a combination of both
  • Possible causes include:
    • Communication problem between gut and brain
    • Previous gut infection
    • Altered bacteria in the gut
    • Stress factors
    • Hyper sensitivity to certain foods


Should I seek help?  You should make an appointment with your doctor if you are experiencing any of the following:

  • Rectal bleeding
  • Weight loss
  • Fever
  • Chills
  • Nighttime symptoms
  • Increased symptoms after 50 years of age


Getting back to normal.  The road to relief is different for everyone, and there are many treatment options available.  The best place to start is with you.

  • Reduce stress
  • Avoid foods that cause symptoms (dietitians can help you with this)
  • Learn what keeping a low-FODMAP diet means for you.

Over the counter medications include:

Prescription Medications Include:


Tried everything?  

Don’t fret, there are several new treatments available.  Contact ClinSearch for information regarding new studies for IBS.